High‑value reagents, reference standards and intermediates for innovative diagnostic systems – developed by ChiroBlock, the specialized synthetic chemistry CRO in Europe.

Chemical Custom Synthesis for Diagnostics – from first‑in‑class molecule to reliable supply

ChiroBlock focuses exclusively on advanced synthetic chemistry, offering end‑to‑end custom synthesis for diagnostic substrates, linkers, labeled standards and other specialty reagents that are not commercially available. Located in Bitterfeld‑Wolfen (Germany), the company bridges the gap between academic discovery and industrial manufacturing for demanding diagnostic applications.

• 25+ years of experience in multi‑step and first‑time syntheses
• Highly qualified team with a majority of PhD chemists and route‑design experts
• Proven track record as a synthetic chemistry CRO for pharma, biotech and diagnostics

Get a project quote for your diagnostic molecule or schedule a consultation with a synthesis expert

Why Chemical Custom Synthesis for Diagnostics needs specialists

Diagnostic assays, IVD systems and POCT platforms require ultra‑pure, structurally well‑characterized and batch‑consistent chemical components. Chemical Custom Synthesis for Diagnostics ensures that substrates, enzyme inhibitors, crosslinkers, labels and reference standards meet stringent performance and regulatory expectations. ChiroBlock is specialized in commercially unavailable, complex and chiral compounds where standard catalog chemistry reaches its limits.

• Exclusive, IP‑protected synthesis of diagnostic key reagents (no catalog sales)
• Design and execution of robust, scalable synthetic routes for critical diagnostic components
• Support for technology transfer to GMP and large‑scale manufacturing partners

Discuss your diagnostic compound with our experts

Services: from route design to diagnostic‑grade delivery

MoleculeFactory – custom synthesis of diagnostic reagents

• Development and execution of synthetic routes for novel substrates, reporters, linkers, tags and internal standards used in diagnostic assays.
• First‑time synthesis (FTS) of research and lead compounds in mg–kg scale for feasibility, method development and assay validation.

ReDesignFactory – route scouting and process optimization

• Retrosynthetic analysis, route scouting and redesign for existing diagnostic molecules to reduce cost, improve robustness or avoid critical reagents.
• Process intensification and up‑scaling concepts for transfer from lab scale to kilo lab and external GMP producers.

Analytics, documentation and supply

• Comprehensive analytical characterization (HPLC, NMR, LC‑MS, GC, purity profiles, impurity tracking) with CoA and supporting data
• Regular supply of exclusive specialty chemicals under IPEC PQG GMP‑aligned conditions for use in sensitive bioprocesses and diagnostic applications.

Request a tailored Chemical Custom Synthesis for Diagnostics proposal

ChiroBlock’s Chemical Custom Synthesis for Diagnostics service is used by R&D organizations that require deep synthetic chemistry expertise and reliable project execution.

• IVD and clinical diagnostics manufacturers seeking proprietary reagents and standards
• Biotech and MedTech companies developing novel diagnostic platforms and biomarkers
• Pharmaceutical and specialty‑chemical companies needing diagnostic reference materials and impurity standards
• R&D groups that need route design, feasibility studies and lab‑scale validation before transferring processes to GMP plants

As an independent, employee‑owned synthetic chemistry CRO founded in 1999, ChiroBlock operates with long‑term, trust‑based collaborations and high scientific standards.

Talk to a senior synthetic chemist about your diagnostic project

Expertise, infrastructure & trust

Documented expertise in complex synthesis

• Thousands of successfully completed custom synthesis projects, including chiral, heterocyclic and highly functionalized structures.
• High success rate in high‑risk and multi‑step projects through systematic route scouting and risk mitigation.

Dedicated infrastructure for synthesis R&D

• Modern synthesis labs, kilo‑lab and pilot areas at the Bitterfeld‑Wolfen site (Germany), optimized for custom synthesis rather than standard production.
• Digital documentation and traceability of raw materials, intermediates and final products for audit‑ready transparency.

Confidentiality and IP protection

• Project‑specific NDAs, customer exclusivity and no internal product line that might compete with clients’ diagnostic portfolios.
• Structured tech‑transfer packages for seamless hand‑over to internal or external manufacturing sites.

Request details on quality, IP and compliance

Summary:

ChiroBlock offers Chemical Custom Synthesis for Diagnostics, covering the design, optimization and execution of synthetic routes for diagnostic reagents, chiral building blocks, labeled standards and specialty intermediates. As a synthetic chemistry CRO, ChiroBlock delivers exclusive, IP‑protected compounds with full analytical documentation, enabling IVD, POCT and clinical diagnostics manufacturers to secure supply, increase assay robustness and accelerate product development.

Strengthen your diagnostic pipeline with expert‑level Chemical Custom Synthesis for Diagnostics – request your project assessment today.